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In inpatient adults with alcohol withdrawal syndrome, does symptom-triggered dosing of a benzodiazepine (BZD) versus fixed-schedule dosing result in lower CIWA-Ar scores and less total BZD use?

Words: 313
Pages: 2
Subject: Nursing

Description

Attach is my PICO question and the articles that I used for my matric table… Attach is the articles that I used. The instructions are as follows and an example of what the professor wants is also attached.

Write a review of the five (5) recent (2016 or later) peer-reviewed journal articles you included on your literature review matrix table.

Include in-text citations and a reference page.

(1 page)

Example

PICO Question:

In inpatient adults with alcohol withdrawal syndrome, does symptom-triggered dosing of a benzodiazepine (BZD) versus fixed-schedule dosing result in lower CIWA-Ar scores and less total BZD use?

Literature Review:

Many of the studies favored the symptom-triggered approach. Several of the articles found that symptom-triggered dosing resulted in less total BZD use and shorter hospitalizations (Hoffman & Weinhouse, 2015; Skinner, 2014; Mirijello et al., 2015; Grgurich et al., 2014; Murdoch & Marsden, 2014; Benson, & Forrest, 2012). Another study found that symptom-triggered therapy resulted in less total BZD use, as well as, shorter duration of use and a reduction in the need of adjunctive medications (Taheri et al., 2014). The work of Hoffman and Weinhouse (2015) found that the symptom-triggered approach resulted in the same or better symptom relief than a fixed-schedule. A study by Duby et al. (2014) focused on critically ill patients and found decreased intensive care unit (ICU) length of stay and less time on mechanical ventilation with symptom-triggered therapy.

Other studies had mixed results. Two studies found that symptom-triggered dosing resulted in lower total BZD use and a shorter duration of use but found no difference in the incidence of complications (Sachdeva et al., 2014; Zeier et al., 2013). The study by Maldonado et al. (2012) found no statistically significant difference between the two dosing types regarding CIWA-Ar scores and total BZD usage. Another study also found no benefit to the symptom-triggered method, with no difference in the total BZD use, length of BZD use, or length of stay (Waye et al., 2015).