Description
Given instructions- Needs to be short and sweet, to the point; stay on topic; no need to repeat question back; no need for a cover sheet. APA 7th edition. 4 questions (250 words per question excludes citations and references). Prescribed textbooks only for referencing:
-Bullock, S., & Hales, M. (2019). Principles of pathophysiology (2nd Ed.) Pearson Australia.
-Bullock, S., & Manias, E . (2017). Fundamentals of pharmacology (8th Ed.). Pearson Australia.
-McCance, K. L., Huether, S. E., Brashers, V. L. & Rote, N. S. (2014). Pathophysiology. The biologic basis for disease in adults and children (6th ed.). Elsevier. US.
-VanMeter, K. C., & Hubert, R. J. (2014). Gould’s pathophysiology for the health professions (5th Ed.). Elsevier. US.
MIMS online (2021).
Q1. Discuss the pathophysiology of osteoarthritis.
Q2. Describe the clinical manifestations of osteoarthritis (joint pain, swollen joints, Bouchard’s nodes, tender joints) and related these to the changes which occur in the musculoskeletal system.
Q3. Discuss the diagnostic procedures for osteoarthritis and how they contribute to diagnosis (ultrasound shows inflammation in the tendons of some of the joints, particularly those containing Bouchard’s nodes and xray indicates osteophytes in numerous joints in patients hands and narrowing of the joint space).
Q4. Explain why capaicin (applied topically 3 to 4 times per day) and ibuprofen 400mg is prescribed (3 times per day) and suitable for treating osteoarthritis. Outline mechanism of action and how these are usually administered.
