Starting from the important study by Lancaster et al (2013), discuss and critically analyse how cerebral organoids can help us better understand neurodevelopment and neurodevelopmental disorders.
In addition, debate how this research established the groundwork for more recent research studies using cerebral organoids to investigate human brain development and neurodevelopmental disorders.
Lancaster, M. A., Renner, M., Martin, C.-A., Wenzel, D., Bicknell, L. S., Hurles, M. E., … Knoblich, J. A. (2013). Cerebral organoids model human brain development and microcephaly. Nature, 501(7467), 373–379. https://doi.org/10.1038/nature12517
This is based on Lancaster’s discovery of the cerebral organoids. Debating it with more recent research later than 2013. Choosing a disorder ie ASD.
