ITP Week 10
PPCP & HTN Health Topic – Activity worksheet
5 mg IV bolus every 2 minutes for 3 doses. Then, 15 minutes after the last IV dose, begin oral therapy
Electronically ordered and signed: Walter Maxwell, MD
a. COLLECT: Define the disease state, what else is it called?
How is the disease state diagnosed? What are risk factors?
b. ASSESS: Do we need to treat it pharmacologically? Can we treat it non pharmacologically in the acute phase? What happens if you do not treat it?
c. PLAN: Is this order appropriate (look up in Clinical Pharmacology) After the acute phase is over – what non-pharmacological treatments should the patient implement?
d. IMPLEMENT: What would be some counseling points (something the pharmacist would say to the patient to help them do well with the medicine)?
e. FOLLOW UP and MONITOR: What would be some monitoring parameters and when do you monitor for each? (what efficacy outcome or ADR should/would the patient, pharmacist or doctor monitor for efficacy and/ or toxicity)
2. (for the order for patient JJ above):
a. What is the concentration of Metoprol as supplied? What is the total dose of Metoprolol, what would be the total volume?
b. What does “bolus” mean? Do you need to compound a dose of Metoprolol?
c. What is the salt form of the Metoprolol injection? Are all oral formulations the same salt form? What’s the difference in the salt forms?
d. When you change the patient to oral form, what dose would you start at and what is the dosing frequency? (specify the salt formulation)
e. Why do you think the dose varies so much between injectable and oral?