Eicosanoids
Based on the attached lecture write a clear biochemical response to the below questions. Do not exceed 2 pages for the responses. You may utilize Peer-reviewed Journal articles as supporting information to answer questions. Format of assignment is AMA. Include at least 3 citations:
A 65 year old retired construction worker is referred to the dialysis clinic following a recent diagnosis of chronic kidney disease due to a prolonged use of of the NSAID Ibuprofen. Explain the biochemical basis of NSAID nephropathy?
- What is the biochemical rationale for the use of low dose aspirin in patients with coronary artery disease? Why is Ibuprofen not a good substituchote for aspirin in this case?
