Tag: Nojima et al.
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Describe where and how the termination of Polymerase II takes place across the genome at the molecular level. Explain the biological significance of the regulation of transcription termination in regard to gene expression.
Description With reference to the research article from Nojima et al., Cell 2015 [1], discuss the relevant data and write a series of paragraphs addressing the following points: a. Briefly describe the mNET-seq technique and explain two advantages and two disadvantages compared to i) RNA Pol II ChIP-seq method and ii) PRO-seq assays. (30%) b.…